Scientific output: UNamur Radiobiology

Publications

2011

  • Heuskin AC, Wéra AC, Riquier H, Michiels C, Bulgheroni A, Jastrzab M, Caccia M, Lucas S. “On the comparison of three methods of assessing beam quality for broad beam in vitro cell irradiation”. Nuclear Instruments and Methods in Physics Research B, 269(24): 3132-3136, (2011).
  • Wéra AC, Riquier H, Heuskin AC, Michiels C, Lucas. “In vitro irradiation station for broad beam radiobiological experiment” in Nuclear Instrument and Methods in Physics Research B, 269:  3120-3124, (2011)

2012

  • Riquier H, Wéra AC, Heuskin AC, Feron O, Lucas S, Michiels C. “Comparison of X-ray and alpha particle effects on a human cancer and endothelial cells: survival curves and gene expression profiles.” Radiotherapy and Oncology 106(3): 397-403.
  • Heuskin AC, Wéra AC, Riquier H, Michiels C, Lucas S. “Low dose hypersensitivity following in vitro charged particle irradiations: is it the same mechanism as with X-ray radiation” (major revision submitted to International Journal of Radiation Biology)
  • Heuskin AC, Wéra AC, Riquier H, Michiels C, Lucas S. ”Hadrontherapy: Toward Computer Simulation of Survival Curves, (submitted to Physics and Medicine in Biology)
  • Heuskin AC, Wéra AC, Riquier H, Michiels C, Lucas S. ” Low dose hypersensitivity and bystander effect are not mutually exclusive in A549 lung adenocarcinoma cells following irradiation with charged particles.”(submitted to Radiation Research)
  • Wéra AC, Heuskin AC, Riquier H, Michiels C, Lucas  S. “Low LET proton irradiation of A549 non-small cell lung adenocarcinoma cells: dose response and RBE determination” Radiation Research 179(3): 273-81

2013

  • A-C Heuskin, C Michiels and S Lucas. "Toward computer simulation of high-LET in vitro survival curves". Phys. Med. Biol. 58, 6495–6510, (2013).
  • Hélène Riquier, Anne-Catherine Wera, Anne-Catherine Heuskin, Olivier Feron, Stéphane Lucas, Carine Michiels. "Comparison of X-ray and alpha particle effects on a human cancer and endothelial cells: Survival curves and gene expression profiles". Radiotherapy and Oncology 106, 397–403, (2013).
  • Anne-Catherine Wéra, Anne-Catherine Heuskin, Hélène Riquier, Carine Michiels and Stéphane Lucas. "Low-LET Proton Irradiation of A549 Non-small Cell Lung Adenocarcinoma Cells: Dose Response and RBE Determination". RADIATION RESEARCH 179, 273–281, (2013).
  • Anne-Catherine Heuskin, Anne-Catherine Wéra, Hélène Riquier, Carine Michiels and Stéphane Lucas. "Low-Dose Hypersensitivity and Bystander Effect are Not Mutually Exclusive in A549 Lung Carcinoma Cells after Irradiation with Charged Particles". RADIATION RESEARCH, 180, 000–000 (2013), accepted for publication.
  • Anne-Catherine Heuskin, Carine Michiels and Stéphane Lucas. "Low dose hypersensitivity following in vitro cell irradiation with charged particles: Is the mechanism the same as with X-ray radiation?" International Journal of Radiation Biology (2013) submitted.

2014

  • Update of reference (2014):
    Low dose hypersensitivity following in vitro cell irradiation with charged particles: Is the mechanism the same as with X-ray radiation?
    Heuskin, A-C., Michiels, C. & Lucas, S. 2014 Dans : International Journal of Radiation Biology. 90, 1, p. 81-9 9 p.

2015

  • Effects of Alpha Particle and Proton Beam Irradiation as Putative Cross-Talk between A549 Cancer Cells and the Endothelial Cells in a Co-Culture System
    Hélène Riquier, Denis Abel, Anne-Catherine Wera, Anne-Catherine Heuskin, Géraldine Genard, Stéphane Lucas and Carine Michiels,
    Cancers 2015, 7, 481-502; doi:10.3390/cancers7010481
Oral presentations

2011

  • RIQUIER PhD Students’Day. Université Catholique de Louvain, Louvain-la-Neuve, Belgique -  20th May 2011. “Comparison of X-ray and alpha particle irradiations on survival fraction and gene expression pattern in human lung adenocarcinoma A549 cells”
  • H. RIQUIER miRNA and cancer. Invited speaker. FNRS-Ecole doctorale thématique en cancérologie expérimentale. Facultés Universitaires Notre-Dame de la Paix, Namur, Belgique - 13th September 2011. “Comparison of X-ray and alpha particle irradiations on survival fraction and gene expression pattern in human lung adenocarcinoma A549 cells and endothelial cells”

2012

  • H. RIQUIER Séminaire Life-Science. Facultés Universitaires Notre-Dame de la Paix, Namur, Belgique – 24th April 2012. “Comparison of X-ray and alpha particle irradiations on survival fraction and gene expression pattern in human lung adenocarcinoma A549 cells and endothelial cells”
  • A.C HEUSKIN, A.C. WERA, H. RIQUIER, C. MICHIELS, S. LUCAS.- Low dose hypersensitivity and bystander effect in A549 lung adenocarcinoma cells following charged particle irradiation - Lowrad, Lyon, France, December 2012
  • A.C HEUSKIN, A.C. WERA, H. RIQUIER, C. MICHIELS, S. LUCAS.- Investigation of low dose hypersensitivity mechanisms following irradiation with charged particles. 1st BHTC in vitro Workshop.- Brussels, Belgium, 25-25 October 2012.
  • A.C. HEUSKIN, A.C. WERA, H. RIQUIER, C. MICHIELS, S. LUCAS.- Hadrontherapy: Toward computer simulation of survival curves.- 1st BHTC in vitro Workshop.- Brussels, Belgium, 25-25 October 2012.

2014

  • Stéphane Lucas , Description of future radiobiology research with a clinical based protontherapy system., International Conference
    "Radiation Damage in Biomolecular Systems: Nanoscale Insights into Ion-Beam Cancer Therapy" (Nano-IBCT 2014), 2014-10-27, Boppard,Germany
  • Stéphane Lucas , In vitro heavy ion radiobiology and related topics, Workshop on Translational Research in Ion Beam Cancer Therapy (TRIBCT), 2014-09-30, University of Aarhus, Aarhus,Denmark
  • Stéphane Lucas, Small accelerator and in vitro hadrontherapy, 2nd BHTC workshop: "Hadrontherapy: from cell to patient", May 23, 2014 - Université de Namur, Namur Belgium.
  • Stéphane Lucas, Hadrontherapy: what can low energy accelerators bring to the field ?, Dynamics of Systems on the Nanoscale, 2014-05-19, Edimbourgh, United Kingdom

Poster presentations

2011

  • Séminaire des jeunes chercheurs Télévie 2012. Université Libre de Bruxelles - Erasme, Belgique – 1st December 2011. Riquier H., Wéra A.-C., Heuskin A.-C., Feron O., Lucas S., Michiels C. “Comparison of X-ray and alpha particle effects on a human cancer and endothelial cells: survival curves and gene expression”
  • miRNA and cancer. Facultés Universitaires Notre-Dame de la Paix, Namur, Belgique - 13th September 2011. Riquier H., Wéra A.-C., Heuskin A.-C., Feron O., Lucas S., Michiels C. “Comparison of X-ray and alpha particle irradiation effects on human lung carcinoma A549 cells”
  • Poster de vulgarisation scientifique lors d’un évènement de récolte de fonds au profit de la recherche contre le cancer. Facultés Universitaires Notre-Dame de la Paix, Namur, Belgique – 1st March 2011. Riquier H., Feron O., Lucas S., Michiels C. “Etude et amélioration du traitement radiothérapeutique”
  • Hallmarks of cancer revisited and the implications for treatment (BACR 2011). Centre hospitalier universitaire de Liège - 5th February 2011. Riquier H., Wéra A.-C., Heuskin A.-C., Feron O., Lucas S., Michiels C. “Comparison of X-ray and alpha particle irradiation effects on human lung carcinoma A549 cells”
  • BPS General scientific meeting 2011 (Namur, 2011): A.C. Wera, A.C. Heuskin, H.Riquier, C. Michiels and S. Lucas: “In vitro irradiation station for broad beam radiobiological applications”

2012

  • The role of imaging in cancer research (BACR 2012). UZ Brussel – Université Libre de Bruxelles, Belgique - 4th February 2012. Riquier H., Wéra A.-C., Heuskin A.-C., Feron O., Lucas S., Michiels C. “Comparison of X-ray and alpha particle effects on a human cancer and endothelial cells: survival curves and gene expression”
  • Heuskin AC, Wéra AC, Riquier H, Michiels C, S. A. Marino, Lucas S. On the need to perform microbeam cell irradiations to get useful data for the development of a predictive Monte Carlo code of survival fraction.10th International Workshop: Microbeam Probes of Cellular Radiation Response, New York
  • Heuskin AC, Wéra AC, Riquier H, Michiels C, S. A. Marino, Lucas S. On the need to perform microbeam cell irradiations to get useful data for the development of a predictive Monte Carlo code of survival fraction. 10th réunion du groupe de contact FNRS “Stress oxydant”: Oxidative stress and genotoxic response, Mons

Bachelor/Master/PhD thesis

2011

  • Gennart I. – Etude des effets des radiations par particules alpha ou rayons X sur les interactions entre cellules tumorales et cellules endothéliales. URBC-NARILIS, University of Namur – FUNDP and LARN – PMR, NARILIS, University of Namur – FUNDP, Belgium. (April 2011). Bachelor report. Supervisor: Riquier H.

2012

  • Abel D. – Radioresistance caused by molecular communication between tumor cells and endothelial cells after proton irradiation. URBC-NARILIS, University of Namur – FUNDP and LARN – PMR, NARILIS, University of Namur – FUNDP, Belgium. (February 2012 until now). Master report. Supervisor: Riquier H.
  • Peerboom N. - Characterisation of a broad carbon ion beam for in vitro cell irradiations: Feasibility study and first biological analyses – FUNDP, Belgium, June 2012. Supervisor: Prof. S. Lucas

Conference Organisation:

2014

  • 2nd BHTC workshop: "Hadrontherapy: from cell to patient", May 23, 2014 - Université de Namur